Protective effect of latex of Calotropis procera in Freund's Complete Adjuvant induced monoarthritis
نویسندگان
چکیده
منابع مشابه
Calotropis procera Latex Extract Affords Protection against Inflammation and Oxidative Stress in Freund's Complete Adjuvant-Induced Monoarthritis in Rats
In view of the well-established anti-inflammatory properties of latex of Calotropis procera (DL), the present study was carried out to evaluate the protective effect of its methanol extract (MeDL) against inflammation and oxidative stress in monoarthritis induced by Freund's complete adjuvant (FCA) in rats. Intra-articular injection of FCA produced inflammation of the joint with a peak effect o...
متن کاملCalotropis procera Latex-Induced Inflammatory Hyperalgesia—Effect of Antiinflammatory Drugs
The milky white latex of plant Calotropis procera produces inflammation of the skin and mucous membranes on accidental exposure. It produces edema on local administration due to the release of histamine and prostaglandins and is associated with hyperalgesia. In the present study we have evaluated the antiedematous and analgesic activity of antiinflammatory drugs against inflammatory response in...
متن کاملProtective effect of aqueous suspension of dried latex of Calotropis procera against oxidative stress and renal damage in diabetic rats.
Calotropis species have been used in the traditional medicinal system for the treatment of diseases of the liver and abdomen. In view of the antioxidant and anti-hyperglycemic properties of an aqueous suspension obtained from the dried latex of Calotropis procera, the present study was carried out to evaluate its efficacy in affording protection against alloxan induced changes in rat kidney. A ...
متن کاملHistamine mediates the pro-inflammatory effect of latex of Calotropis procera in rats.
INTRODUCTION Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known. In present study we have pharmacologically characterized the inflammation induced by latex of C. procera in a rat paw edema model and determined the role of histamine in late...
متن کاملInvolvement of prostaglandins in inflammation induced by latex of Calotropis procera.
INTRODUCTION The aerial parts of the plant Calotropis procera produce milky white latex that causes inflammation of the skin and mucous membranes. Prostaglandins are one of the mediators released in an inflammatory response following induction of cyclooxygenase (COX). In the present study, we have evaluated the role of prostaglandins in inflammatory response elicited by the latex of C. procera....
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ژورنال
عنوان ژورنال: Phytotherapy Research
سال: 2008
ISSN: 0951-418X
DOI: 10.1002/ptr.2270